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Alien Syndrome is a scrolling shooter arcade conversion.

Your job is to run around and rescue all the captives and make it to the escape hatch before the time bomb explodes. Then face the mother alien at the end of the level.

You can play as a single player or two people, taking turns (Player 2 starts the game after Player 1 dies and vice versa).


Alien Syndrome NES Starting a new game
Alien Syndrome Atari ST Progress map
Alien Syndrome Commodore 64 Character Selection
Alien Syndrome MSX Killed by the maggot-aliens

Promo Images

There are no promo images for this game

Alternate Titles

  • "エイリアンシンドローム" -- Japanese spelling

Part of the Following Group

User Reviews

Run around the spaceship, rescue your friends, and shoot the alien bastards SEGA Master System *Katakis* (38333)
Sweet cooperative alien-blasting action NES Multimedia Mike (19084)
A close rendition of the original SEGA Master System James Evans (42)
Good game, tough bosses. SEGA Master System Ash_1 (55)

Critic Reviews

The Games Machine (UK) Commodore 64 Jul, 1988 89 out of 100 89
Zero Atari ST Dec, 1989 83 out of 100 83
Zero Amiga Dec, 1989 83 out of 100 83
Your Sinclair ZX Spectrum Nov, 1988 8 out of 10 80
Power Play Atari ST Jul, 1988 7.5 out of 10 75
Power Play Commodore 64 Jul, 1988 7 out of 10 70
Video Game Den NES Jan 02, 2011 3 Stars3 Stars3 Stars3 Stars3 Stars 60
ACE (Advanced Computer Entertainment) Atari ST Nov, 1989 3 Stars3 Stars3 Stars3 Stars3 Stars 60
ACE (Advanced Computer Entertainment) SEGA Master System May, 1988 564 out of 1000 56
The Video Game Critic SEGA Master System Mar 13, 2005 D 25


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Sound effect

The opening screen of Alien Syndrome features a digitized sound effect through the PC Speaker. However, the 1-bit method used to reproduce the sound effect is so poor that you can't discern what the sound is supposed to be.
Contributed to by Quapil (4720), Corn Popper (69214), PCGamer77 (3001), FatherJack (58479), Martin Smith (62786), Terok Nor (24037), Servo (55768), Игги Друге (45000), *Katakis* (38333) and Yakumo (419)