Trivia
The original idea behind the Questprobe series was to have twelve games, each with a corresponding comic book created my Marvel Comics. The first three games and their comics, featuring the Hulk, Spider-Man and the Fantastic Four's Human Torch and Thing, were released but Adventure International went bankrupt before the fourth game, featuring the X-Men, was completed. Marvel had completed the comic book and, years later, released it as part of their Marvel Fanfare series.
The game's documentation says that it will not run with any DOS version higher than 2.10.
To get the game to run under windows 95, you'll need to do a little hacking. With a hex editor, change the two bytes in the main exe file from "??" at offset AEA4 and AEA5 to "52"
It appears that the original game code was calling a very old DOS open file function that supported wildcards in the filename. It was trying to open the file "SPL52.DAT" using "SPL??.DAT" as a parameter.
Since there is only 1 SPLxx.DAT file used in the game, hard coding the ??'s to 52 works just fine!