Dr. Mario

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Game Boy Advance
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In this Tetris-style game, you play as Dr. Mario, who must drop differently coloured pills onto viruses to remove them from the bottle. Each pill is split into two, with each side being of one of three different colours, red, blue or yellow. Align three pills of the same colour to a virus of the corresponding colour (or any combination of pills and viruses totaling four or more) and it will be removed from the bottle, along with the aligned pills. The level is cleared when there are no viruses left, and the game is over when the pills reach the top and Dr. Mario can't drop any more pills.

Included in the game is the normal mode, a time trial, and a two player battle mode to see who can remove the most viruses.


Dr. Mario SNES Playing Vs. Com on blue virus level.
Dr. Mario Arcade Well done
Dr. Mario Game Boy Setup
Dr. Mario SNES 1 player game settings menu

Alternate Titles

  • "Virus" -- Working title
  • "ドクターマリオ" -- Japanese spelling

Part of the Following Groups

User Reviews

Tetris leveled up! NES Pixelspeech (955)
Best mindless entertainment game since Tetris. NES Multimedia Mike (17555)
A classic puzzle game which still remains enjoyable today NES Jon Collins (28)
Play "Tetris" with Mario. Game Boy Michael B (341)
Everybody (especially Tetris fans) will find themselves addicted to this game in minutes. Game Boy pocketgamer2000 (22)

Critic Reviews

VideoGame Game Boy Jul, 1991 5 Stars5 Stars5 Stars5 Stars5 Stars 100
Consoles Plus Game Boy Sep, 1991 95 out of 100 95
NES Archives NES Mar 22, 2008 A- 91
NES Times NES Feb 15, 2008 9 out of 10 90
Mean Machines NES Feb, 1991 88 out of 100 88
Mean Machines Game Boy Feb, 1991 87 out of 100 87
Pixel-Heroes.de SNES Apr, 2006 8 out of 10 80
GameSpot Game Boy Advance Nov 02, 2004 7.4 out of 10 74
Electronic Gaming Monthly (EGM) Game Boy Nov, 1990 23 out of 40 58
Jeuxvideo.com Game Boy Advance Jan 12, 2005 8 out of 20 40


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1001 Video Games

Dr. Mario appears in the book 1001 Video Games You Must Play Before You Die by General Editor Tony Mott.


  • Game Informer
    • August 2001 (Issue #100) - #76 in the "Top 100 Games of All Time" poll

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Contributed to by Michael Cassidy (13987), Kartanym (10755) and gamewarrior (5062)