Dr. Mario

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Game Boy Advance
Nintendo 3DS
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In this Tetris-style game, you play as Dr. Mario, who must drop differently coloured pills onto viruses to remove them from the bottle. Each pill is split into two, with each side being of one of three different colours, red, blue or yellow. Align three pills of the same colour to a virus of the corresponding colour (or any combination of pills and viruses totaling four or more) and it will be removed from the bottle, along with the aligned pills. The level is cleared when there are no viruses left, and the game is over when the pills reach the top and Dr. Mario can't drop any more pills.

Included in the game is the normal mode, a time trial, and a two player battle mode to see who can remove the most viruses.


Dr. Mario Game Boy Setup
Dr. Mario SNES Now I am eliminating the blue virus.
Dr. Mario Arcade Lets get rid of the germs
Dr. Mario NES After beating certain levels the player is treated to a cutscene like this

Alternate Titles

  • "Virus" -- Working title
  • "ドクターマリオ" -- Japanese spelling

Part of the Following Groups

User Reviews

Tetris leveled up! NES Pixelspeech (955)
Best mindless entertainment game since Tetris. NES Multimedia Mike (17555)
A classic puzzle game which still remains enjoyable today NES Jon Collins (28)
Play "Tetris" with Mario. Game Boy Michael B (341)
Everybody (especially Tetris fans) will find themselves addicted to this game in minutes. Game Boy pocketgamer2000 (22)

Critic Reviews

NES Archives NES Mar 22, 2008 A- 91
1UP! NES Dec 06, 2001 90 out of 100 90
Mean Machines Game Boy Feb, 1991 87 out of 100 87
Video Games Game Boy Jun, 1991 83 out of 100 83
Megablast Game Boy 1992 82 out of 100 82
Raze Game Boy Dec, 1990 81 out of 100 81
GameSpot Game Boy Advance Nov 02, 2004 7.4 out of 10 74
neXGam NES 2002 6.8 out of 10 68
JeuxActu Game Boy Advance Jan 31, 2005 10 out of 20 50
Jeuxvideo.com Game Boy Advance Jan 12, 2005 8 out of 20 40


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1001 Video Games

Dr. Mario appears in the book 1001 Video Games You Must Play Before You Die by General Editor Tony Mott.


  • Game Informer
    • August 2001 (Issue #100) - #76 in the "Top 100 Games of All Time" poll

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Contributed to by Michael Cassidy (14096), Kartanym (10753) and gamewarrior (5062)