Ghoul Patrol was marketed as a sequel to Zombies ate my Neighbors, and though the gameplay, music, and overall style are quite similar, it was actually intended as a completely unrelated game. As "Zombies" designer Mike Ebert explains:
"What happened is they had another game that was kind of lost and struggling, so they changed it into "Ghoul Patrol" and called it a sequel to ZAMN in hopes that it would actually sell. It really never was supposed to have anything to do with Zombies Ate My Neighbors. I was shocked when I first saw it in the test department and the characters looked like the Z.A.M.N characters".