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For those of you who have played the original Dr. Mario for the NES and/or Game Boy, you are most likely going to love the updated N64 version. Like in the NES/GB game you must match up four of the same colors horazontally or vertically to eliminate the pills and viruses. One of the many new features in this game is a multiplayer mode where up to four people can play. And the great thing about the multiplayer mode is that you don't need four players to engage in a four player free for all, team battle, or four player flash.
The Video Game Critic
It's the same Dr. Mario that's been released on the SNES, but this one contains more options and playing modes. If you enjoy puzzle games and you haven't tried Dr. Mario yet, you need to pick this up in a hurry. For the record, this is one of my wife's favorite video games of all time.
Game Informer Magazine
For those of you who haven't already traded in your N64, Nintendo is rewarding your loyalty with Dr. Mario 64, a revival of the classic puzzle game that presided over just about every other previous Nintendo console. I was always a big fan of tossing two-toned pills on like-colored viruses, especially on the NES. I had to strain my eyes a little while engaging in the new four-player simultaneous action in this update, but Dr. Mario 64 is one of the better multiplayer experiences on the console. The rewards you unlock and the different character paths in the game's Story mode make it worth playing through.
Game Informer Magazine
The doctor is in, and his game is frustration. For those of you who haven’t invested time in Dr. Mario’s previous exploits, I strongly suggest you pop some pills with the newly developed N64 release. The same as it ever was, Dr. Mario boggles the mind more so than any other puzzle game on the market, and is demanding of precise timing and dead-on accuracy. Addiction is immediate and withdrawl is impossible. The new game modes and harrowing difficulty will keep you hooked for months.
Adrenaline Vault, The (AVault)
The Dr. Mario franchise has never been renowned for its groundbreaking graphics or audio, and Dr. Mario 64 is not an exception to this rule. Fortunately, much of this ground is made up by solid gameplay and a wickedly decisive AI that won’t give you an inch at its harder levels. This is particularly important in the N64 version of the franchise because most of the modes are competitive; and you can even round out a four-player game with a computer player without noticing a major skill deficiency. Essentially, you’re getting more of the same with this package, but it’s easily the most complete and entertaining version of this franchise yet.
Dr. Mario 64 is one of those games you think you'll only be playing for a few minutes but will turn into an hour or so (especially the fun four-player team battle mode). But at the end of the day, there's not a lot of meat here to keep coming back to, plus it really doesn't do much to push the Dr. Mario game series, or puzzle genre, ahead.
I must admit that while Dr. Mario's medical background is shady and unoriginal, his procedural methods can be fun. It's a love or hate affair. Those who've never had an appointment with the doctor may take to it, but others who in the past made regular visits might feel that he hasn't kept up with the times. Mario - I'm onto you. Think you can run around playing doctor while hocking your sugar pills? You might be offering your services for a seemingly affordable $29.95, but didn't we already try this medicine? Better get Lawyer Luigi on the phone.
To be honest, Dr. Mario 64 is just about everything I expected it to be. It was obviously an effort by Nintendo to get a game out for the month of April, and get it out quickly. There have been virtually zero upgrades outside of the four-player versus modes, which lends little reason not to go back and play SNES version which featured both Dr. Mario and Tetris. If you're dying for a multiplayer puzzle game that you can play with three friends, then Dr. Mario 64 is well worth it for around $30. Otherwise, I suggest sticking with The New Tetris or the well Pokémon Puzzle League. Dr. Mario 64 is more or less Nintendo's way of using Mario's name to sell a port of a very old game. This doctor's Ph.D. expired long ago.