DevelopmentOne of the first games announced for the then-announced CD-ROM addon for the SNES. Nintendo eventually gave up trying to get the peripheral off the ground after the deal with Phillips to make the drive fell flat. Square eventually released a tooled-down version, which pushed the SNES hardware constantly (hence the slowdown and lack of multiple enemies onscreen), and overall left Square bitter for having to go through the process of downgrading its game. This probably was one of the reasons Square decided to bail on Nintendo (and its then-upcoming N64 console) and take its multimillion seller, Final Fantasy VII, with it (which was first announced for the N64).
Ironically, Square signed the deal to bring the game to the PlayStation with Sony, which was the original partner for the SNES CD drive, but was publicly stabbed in the back by Nintendo with the Phillips deal. The CD drive technology that Sony had been working on for the SNES, was then used to create the PlayStation itself.
EnemiesDue to technical limitations, only three enemies can ever be on the screen at one time. Sneaky players can use this to their advantage and keep 'easy' enemies alive to block the spawning of more powerful ones. The merchant cat Neko, is also affected by this and may not always appear during busy combat.
KillroyIn the original Japanese version, Killroy has a chainsaw when fighting him the second time. In all Western versions, he is just a re-coloured version of the first encounter.
MultiplayerSecret of Mana is quite possibly the first RPG game to support 3 Players. It is certainly the only one on SNES that does (along with it's sequel, which was never officially translated). A multitap is required for the third player.
SlimeThe Slime bosses are the trickiest enemies in the game, not because they're difficult, but because they're so buggy. When fighting one of these bosses it's possible to slow the framerate to a crawl, freeze the game or in extreme cases, wipe the contents from your saved battery backup.
Contributed by MaiZure (114) on Feb 19, 2003. [revised by : CrankyStorming (2613) and Patrick Bregger (98677)]. -- edit trivia