Due to Nintendo of America's policies on religious imagery and usage in games, the US versions of the NES and SNES editions of the game have the "Houses of Worship" area of ports changed to "The Round Earth Society". The option there that lets the player "Pray" has also been changed to "Study", however both versions of the game allow the player to donate money towards the organization.
Uncharted Waters 2: New Horizons has a lot of bugs and 'un-user-friendly features', uncommon for a game published by Koei. Anyway, here's one irritating bug I've found out: Half to 3/4 of your crew suddenly vanish in thin air while your sailing. This happend to me in Northern Europe near Antwerp. No idea why this occured (not because of rations) nor where they went...
The game takes place in the 16th century, but the city known as Istanbul in the game doesn't take this name until 1930. It should be called Constantinople