From the ingame intro:

"Doctor Octopus is plotting the crowning caper of his criminal career... to rule the world. He has reunited the Sinister Six and with these super-villains together again, nothing stands in their way - except Spider-Man!"

Spider-Man: Return of the Sinister Six is a side-scrolling game which puts you in the role of Spidey throughout six levels against Electro, Sandman, Mysterio, Vulture, Hobgoblin and Doctor Octopus respectively. Some puzzle solving (like finding a key) is necessary to beat some levels. Spidey can duck jump, climb walls, punch, shoot webs to swing (by pressing punch and jump together) and perform a jump kick (by pressing the punch button twice). Collecting web cartridges allows Spidey to shoot limited web projectiles.

Although hard to die, Spidey has only one life, there are no items to recharge life (but killing some guys will do so) and only one continue.

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Part of the Following Groups

Merchant	Title	Platform	Price
	Spider-Man: Return of the Sinister Six	NES	$5.44
	Spider-Man: Return of the Sinister Six
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User Reviews

Poor Spidey, What Did They Do To Ya?	NES	Edward Brown (308)
An inferior port of an above average NES game.	SEGA Master System	Magus_X (104)
A decent NES Spider-Man	NES	Magus_X (104)

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The Press Says

N-Force	NES	Oct, 1992	85 out of 100	85
GamePro (US)	NES	Oct, 1992	4 out of 5	80
Nintendo Magazine System UK	NES	1992	70 out of 100	70
Power Unlimited	Game Gear	Sep, 1993	7 out of 10	70
The Video Game Critic	NES	Apr 17, 2006	D	25