In the PC version of the game, two cheat codes, one that made you have big head and feet and another that made your character tiny-sized, are disabled by the 1.1 patch to the game. The reason for this is unknown, possibly to improve game stability or something like that.
This game has several cheat codes that allow you to play the game as a variety of characters, such as thugs, security guards, the Shocker, and a motorcycle cop named Captain Stacey with a striking resemblance to Marvel kingpin Stan Lee.
One code allowed you to play the game as Mary Jane (the only female playable character), but this code was apparently disabled in later production copies of the game. A possible reason for this is that in the game's ending you see Mary Jane and your character kissing, so if you play as Mary Jane you end up with her frenching herself. Perhaps the developers felt that having two women making out in their game would alienate potential buyers (or, more likely, the parents of potential buyers), considering the family demographic this game is targeted at.
In the X-Box version of this game, there are two extra levels where you fight Kraven the Hunter that isn't in the PS2, Gamecube, or PC versions.