| Echoes+ | Fire OS | 2015 | Binary Zoo |
| Ecofish | Android | 2012 | Eclipse Games SC |
| Eden: Renaissance | iPad, iPhone | 2017 | Last Kind Limited, The |
| Edge | GameStick, tvOS | 2009 | Connect2Media, Mobigame S.A.R.L., Rainy Frog LLC, Two Tribes Publishing B.V. |
| Edge Extended | tvOS | 2011 | Advanced Mobile Applications Ltd, Mobigame S.A.R.L. |
| Edmund | Windows | 2009 | |
| Edna Bricht Aus: Sammler Edition | Windows | 2011 | Daedalic Entertainment GmbH |
| Edna & Harvey: Harvey's New Eyes | Macintosh | 2011 | ak tronic Software & Services GmbH, Daedalic Entertainment GmbH, rondomedia Marketing & Vertriebs GmbH |
| Edna & Harvey: The Breakout (Collector's Edition) | Windows | 2011 | Lace Mamba Global Ltd. |
| Eduardo the Samurai Toaster | Wii | 2009 | Semnat Studios LLC |
| Eets: Hunger. It's emotional. | Macintosh | 2006 | Eclypse, Frogster Interactive Pictures AG, Klei Entertainment Inc. |
| Eggggg: The Platform Puker | Android, iPad, iPhone, tvOS | 2016 | Hyper Games AS |
| Egglia: Legend of the Redcap | Android, iPad, iPhone | 2017 | DMM.com Co., Ltd. |
| Egypt II: The Heliopolis Prophecy | Macintosh | 2000 | 1C Company, Cryo Interactive Entertainment, Dice Multi Media Europe B.V., DreamCatcher Interactive Inc., Microïds |
| Eight Legged Freaks | Macintosh | 2002 | Warner Bros. |
| The Elder Scrolls IV: Oblivion - Game of the Year Edition | PlayStation 3, Windows, Xbox 360 | 2007 | 1C Company, 2K Games, Inc., ak tronic Software & Services GmbH, Bethesda Softworks LLC |
| The Elder Scrolls: Legends - Heroes of Skyrim | iPhone | 2017 | Bethesda Softworks LLC, ZeniMax Media Inc. |
| The Elder Scrolls Online: Tamriel Unlimited | Macintosh, PlayStation 4, Windows, Xbox One | 2015 | Bethesda Softworks LLC, ZeniMax Europe Ltd. |
| The Elder Scrolls Online | Macintosh, Windows | 2014 | Bethesda Softworks LLC |
| Electronic Super Joy | PlayStation 4, Xbox One | 2016 | LOOT Interactive, LLC |
| Element4l | Linux | 2013 | I-Illusions |
| Elephant Rave | iPhone | 2008 | jmtb02 Studios, Shillington & Sons |
| Elevator Action | Wii | 1983 | CGE Services Corporation, MediaKite Distribution Inc., Nidecom Soft, Quicksilva Ltd., SEGA Enterprises Ltd., Square Enix Co., Ltd., Taito America Corporation, Taito Corporation |
| Elf Tales | J2ME | 2003 | Trecision S.p.A. |
| Eliss Infinity | Android, iPad, iPhone | 2014 | Finji, Little Eyes LLC |
Game Title