Join our Discord to chat with fellow friendly gamers and our knowledgeable contributors!

Not an American user?


Alien Syndrome is a scrolling shooter.

Your job is to run around and rescue all the captives and make it to the escape hatch before the time bomb explodes. Then face the mother alien at the end of the level.


Alien Syndrome Commodore 64 that annoying thing won't die too easily
Alien Syndrome ZX Spectrum Stop the tape then press enter
Alien Syndrome DOS Title screen
Alien Syndrome Amiga Mission Briefing

Promo Images

There are no promo images for this game

Alternate Titles

  • "エイリアンシンドローム" -- Japanese spelling

Part of the Following Groups

User Reviews

Sweet cooperative alien-blasting action NES Multimedia Mike (20634)

Critic Reviews

Crash! ZX Spectrum Oct, 1988 90 out of 100 90
Crash! ZX Spectrum Oct, 1989 84 out of 100 84
Computer and Video Games (CVG) Atari ST Nov, 1989 79 out of 100 79
Power Play Atari ST Jul, 1988 7.5 out of 10 75
Computer and Video Games (CVG) Commodore 64 May, 1988 7 out of 10 70
Defunct Games NES Jun 05, 2012 B- 67
Video Game Den NES Jan 02, 2011 3 Stars3 Stars3 Stars3 Stars3 Stars 60
ACE (Advanced Computer Entertainment) Amiga Nov, 1989 3 Stars3 Stars3 Stars3 Stars3 Stars 60
NES Player NES 2001 3 out of 5 60
Computer and Video Games (CVG) Amstrad CPC Nov, 1989 51 out of 100 51


Topic # Posts Last Post
Incorrect platform 2 vedder (51029)
May 05, 2019


Sound effect

The opening screen of Alien Syndrome features a digitized sound effect through the PC Speaker. However, the 1-bit method used to reproduce the sound effect is so poor that you can't discern what the sound is supposed to be.
Contributed to by Quapil (5455), Corn Popper (69066), FatherJack (62732), Martin Smith (74278), Terok Nor (30414), Servo (57366), Игги Друге (46331), Katakis | カタキス (41931) and Yakumo (472)