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Alien Syndrome is a scrolling shooter arcade conversion.

Your job is to run around and rescue all the captives and make it to the escape hatch before the time bomb explodes. Then face the mother alien at the end of the level.

You can play as a single player or two people, taking turns (Player 2 starts the game after Player 1 dies and vice versa).


Alien Syndrome Atari ST Title screen
Alien Syndrome DOS Bringing up the map by walking into the wall marked "Map".
Alien Syndrome DOS In-game
Alien Syndrome NES The opening sequence

Promo Images

There are no promo images for this game

Alternate Titles

  • "エイリアンシンドローム" -- Japanese spelling

Part of the Following Groups

User Reviews

Run around the spaceship, rescue your friends, and shoot the alien bastards SEGA Master System Katakis | カタキス (39781)
Sweet cooperative alien-blasting action NES Multimedia Mike (19855)
A close rendition of the original SEGA Master System James Evans (42)
Good game, tough bosses. SEGA Master System Ash_1 (76)

Critic Reviews

Your Sinclair ZX Spectrum Nov, 1988 8 out of 10 80
Gamezone (Germany) Amiga May 07, 2007 6.8 out of 10 68
The Games Machine (UK) SEGA Master System Mar, 1988 61 out of 100 61
ACE (Advanced Computer Entertainment) Atari ST Nov, 1989 3 Stars3 Stars3 Stars3 Stars3 Stars 60
NES Player NES 2001 3 out of 5 60
Video Game Den NES Jan 02, 2011 3 Stars3 Stars3 Stars3 Stars3 Stars 60
ACE (Advanced Computer Entertainment) Amiga Nov, 1989 3 Stars3 Stars3 Stars3 Stars3 Stars 60
ACE (Advanced Computer Entertainment) SEGA Master System May, 1988 564 out of 1000 56
The Video Game Critic NES Apr 24, 2005 C- 42
Game Freaks 365 SEGA Master System Aug 30, 2005 3 out of 10 30


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Sound effect

The opening screen of Alien Syndrome features a digitized sound effect through the PC Speaker. However, the 1-bit method used to reproduce the sound effect is so poor that you can't discern what the sound is supposed to be.
Contributed to by Quapil (4825), Corn Popper (69350), PCGamer77 (3233), 666gonzo666 (61765), FatherJack (62754), Martin Smith (66864), Terok Nor (27133), Servo (57393), Игги Друге (46422), Katakis | カタキス (39781) and Yakumo (473)