Bejeweled Blitz Live is a reworked version of Bejeweled Blitz. Just like all other games in the Bejeweled series the gameplay is centered around swapping gems on a board to create matches of three gems of the same type. They explode and new ones drop down from the top, often forming chain reactions. Matches of four gems or more introduce special gems and additional points. It contains both the original Classic game mechanic with swapping a gem vertically or horizontally, as well as the Twist mode where a group of four gems is rotated left or right without the need to create a match for each action. For this XBLA version the quick gameplay is supported through separate buttons and keys to move the cursor and to swap and rotate at the same time to mimic the speed the game can be played with a mouse.
Multiplayer is available locally through split-screen or online for both the Classic and Twist mode. It can be played as a 60-second time limit game or in a head-to-head battle. Online multiplayer is also available for up to sixteen players simultaneously in the Party mode. A grid on the left side of the screen shows the position of each player in the ranking based on the points gathered so competitors can be tracked without having to see their board.