The third part of the Blood trilogy, this game is set at the very dawn of time: Mere nanoseconds after the Big Bang. This is where the time-travelling shenanigans of the second game ended up. Now you, Commander Blood, are the only evolved lifeform in the entire universe, and it's up to you to correct the problems you've caused and guide the development of all other life. You start the game with a few amoeba-esque creatures at your disposal. Find a planet to put them on, then take care of them, help them migrate to other worlds, evolve and mutate. Big Bug Bang: Le Retour de Commander Blood uses the exact same interface and many of the same graphical sequences as its predecessor Commander Blood. It is a surreal, galaxy-spanning, humorous sci-fi adventure.
This was a very low-profile game, released with minimal advertising in France and Canada only. Although the Microfolie's website claimed the game was going to be available in a variety of languages, as of 2001 it was apparently only released in a French-language version. Even if Captain Blood-fans from other countries manage to obtain a copy of this rare title, they'll probably need the assistance of a dictionary.
However, two hints suggest the game was already localized in English at the time of its release: the credits are entirely in English, and those same credits mention that Liam Gavin and Johan Robson were responsible for the game's "adaptation" (read: English localization).