Private detective Vicki Nelson has to solve a series of missing persons cases with the help of a 450-year-old vampire.
Blood Ties is a standard hidden object game tied to an obscure Canadian TV series license. As is always the case with these games, the objective is to find all the objects of a list in a screen cluttered with things.
The game is segmented in investigation cases with a number of locations (each with one screen with a list) and a fixed time limit. Three hints are provided at the start of each case. They highlight the position of listed objects when clicked. Pentagrams add an extra hint when found.