Deer Avenger 3D brings the comical Deer Avenger series into 3D perspective. In this installment, our hero Bambo seems to have found happiness with a new doe bride, while believing that the dreaded human hunters have forever been vanquished. Just as the pair is about to engage in intimacy, small woodland creatures appear at their window to urgently warn of the hunters' return. Bambo's bride laments that she can't get into the mood while the creatures of the wilderness are threatened. With a cry of soul-wrenching anguish, Bambo finds himself curiously motivated to strike out to dispatch the bipedal enemies once more.
Bambo's base of operations is his cabin. He can admire his trophy wall or arm up and head out into the snow wilderness. In the wilderness, he can walk, run, or jump around the terrain; lay out lures for the hunters such as pizza and beer; collect fart powerups; and generally wait until a hunter announces their presence. Once a hunter is in the area, use the stereo sound effects or the radar fart to track the hunter. Shoot or be shot, and endeavor to collect the heads of all 7 hunters for your trophy wall. Further, once you take out a hunter, you gain their weapon and can select from among your accumulated weapons during your next hunting round. There are also some harmless humans who are in tune with nature that you must take care not to kill or its game over.