While being welcomed to the virtual amusement park Disney Universe by VIC (Virtual Information Cube), a virus of sorts named Hexx infects the system causing chaos to this virtual world. Now it's up to the player to defeat Hexx and restore order to this virtual playground.
Disney Universe features six worlds based on Disney and Pixar movie properties. The worlds featured are Pirates of the Caribbean, Alice, Lion King, Monsters, Inc., Aladdin, and Wall-E. The worlds are broken up into three sections, with a guest that needs to be freed at the end of each section. Players have to solve puzzles and fight enemies to progress further similar to the gameplay found in Travellers TalesLEGO games. Players need to also collect Mickey Mouse head icons which are used as currency to unlock the worlds and Disney-themed character costumes.