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Alien Syndrome is a scrolling shooter arcade conversion.

Your job is to run around and rescue all the captives and make it to the escape hatch before the time bomb explodes. Then face the mother alien at the end of the level.

You can play as a single player or two people, taking turns (Player 2 starts the game after Player 1 dies and vice versa).


Alien Syndrome DOS The only way to harm it is to shoot it's opening. Yes I realize how that sounds.
Alien Syndrome DOS Opening Title with credits
Alien Syndrome DOS Character selection
Alien Syndrome DOS Bringing up the map by walking into the wall marked "Map".

Promo Images

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Alternate Titles

  • "エイリアンシンドローム" -- Japanese spelling

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Sound effect

The opening screen of Alien Syndrome features a digitized sound effect through the PC Speaker. However, the 1-bit method used to reproduce the sound effect is so poor that you can't discern what the sound is supposed to be.
Yakumo (473) added Alien Syndrome (DOS) on Mar 11, 2000
Other platforms contributed by Quapil (4825), Corn Popper (69379), PCGamer77 (3234), FatherJack (62754), Martin Smith (66852), Terok Nor (26757), Servo (57398), Игги Друге (46428) and Katakis | カタキス (39490)