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Alien Syndrome is a scrolling shooter.

Your job is to run around and rescue all the captives and make it to the escape hatch before the time bomb explodes. Then face the mother alien at the end of the level.


Alien Syndrome DOS Game options
Alien Syndrome DOS Opening Title with credits
Alien Syndrome DOS Opening Title
Alien Syndrome DOS The only way to harm it is to shoot it's opening. Yes I realize how that sounds.

Promo Images

Alien Syndrome Magazine Advertisement

Alternate Titles

  • "エイリアンシンドローム" -- Japanese spelling

Part of the Following Groups

User Reviews

There are no reviews for the DOS release of this game. You can use the links below to write your own review or read reviews for the other platforms of this game.

Critic Reviews

There are no critic reviews for this game.


Topic # Posts Last Post
Published by is incorrect 2 Hergezod (15417)
Jul 07, 2021
Incorrect platform 2 vedder (55009)
May 05, 2019


Sound effect

The opening screen of Alien Syndrome features a digitized sound effect through the PC Speaker. However, the 1-bit method used to reproduce the sound effect is so poor that you can't discern what the sound is supposed to be.
Yakumo (472) added Alien Syndrome (DOS) on Mar 11, 2000
Other platforms contributed by Quapil (5475), Corn Popper (69005), FatherJack (62725), Martin Smith (76544), Terok Nor (31686), Servo (57358), Игги Друге (46321) and Katakis | カタキス (42253)