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In this Tetris-style game, you play as Dr. Mario, who must drop differently coloured pills onto viruses to remove them from the bottle. Each pill is split into two, with each side being of one of three different colours, red, blue or yellow. Align three pills of the same colour to a virus of the corresponding colour (or any combination of pills and viruses totaling four or more) and it will be removed from the bottle, along with the aligned pills. The level is cleared when there are no viruses left, and the game is over when the pills reach the top and Dr. Mario can't drop any more pills.

Included in the game is the normal mode, a time trial, and a two player battle mode to see who can remove the most viruses.


Dr. Mario NES You can get further than 20 lvl but there won't be any changes
Dr. Mario NES Depending on the level and speed setting a different creature will fly by
Dr. Mario Arcade Lets get rid of the germs
Dr. Mario Game Boy Gameplay on Game Boy Color.

Promo Images

Dr. Mario Screenshot
Dr. Mario Screenshot
Dr. Mario Screenshot
Dr. Mario Screenshot

Alternate Titles

  • "Virus" -- Working title
  • "ドクターマリオ" -- Japanese spelling
  • "닥터 마리오" -- Korean spelling (Hangul)

Part of the Following Groups

User Reviews

Tetris leveled up! NES Asinine (1006)
Best mindless entertainment game since Tetris. NES Multimedia Mike (20410)
A classic puzzle game which still remains enjoyable today NES Jon Collins (28)
Play "Tetris" with Mario. Game Boy Michael B (357)
Everybody (especially Tetris fans) will find themselves addicted to this game in minutes. Game Boy pocketgamer2000 (22)

Critic Reviews

Consoles Plus Game Boy Sep, 1991 95 out of 100 95
NES Archives NES Mar 22, 2008 A- 91
Nintendo Magasinet (Sweden) NES Jun, 1991 4.5 out of 5 90
Power Play Game Boy Oct, 1990 83 out of 100 83
Game Freaks 365 NES 2005 7.6 out of 10 76
IGN Game Boy Advance Oct 26, 2004 7 out of 10 70
64 Power / big.N / N Games Game Boy Advance Mar, 2005 70 out of 100 70
Play Time NES Jun, 1991 65 out of 100 65
Total!! UK Magazine Game Boy Jan, 1992 64 out of 100 64
Game Freaks 365 Game Boy Advance 2004 6 out of 10 60


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1001 Video Games

Dr. Mario appears in the book 1001 Video Games You Must Play Before You Die by General Editor Tony Mott.


  • Game Informer
    • August 2001 (Issue #100) - #76 in the "Top 100 Games of All Time" poll

Related Web Sites

Contributed to by Michael Cassidy (21142), Kam1Kaz3NL77 (266614), Kartanym (12757) and gamewarrior (5048)