Mary Shelly's Frankenstein is an adventure/fighting hybrid based on the 1994 film of the same name. You play as Frankenstein's monster and begin in the lab, where your creator rejects and banishes you in a dialogue sequence. From there, you must escape the village and try to find meaning in a hostile world. Subsequent levels mirror the general story arc of the film and novel.
The game plays through three distinct modes:
Exploration Mode takes place inside buildings, and gives you a side-scrolling view of the Monster. Like a standard adventure, you can examine nearby objects and add them to a limited inventory. You use those items to solve puzzles or open up new pathways. Should you encounter a hostile foe in this mode, you will automatically switch to Combat Mode.
Combat Mode plays and looks like a standard 2-D fighting game. You have buttons to punch, kick, or block, and corresponding D-pad directions that activate different moves. Your goal is to drain your opponent's energy while preserving your own. Winning the fight allows you to continue on.
Long View Mode is an isometric travel view similar to an RPG. Here, you search for new buildings to enter or navigate mazes (such as a forest).
The game shifts between hand-drawn art and 3-D computer graphics. Video clips from the film also introduce the game, and play at critical plot points.