NaissanceE begins with the words "Lucy is lost". Then the player is alone in a (mostly) black-white environment with abstract architecture, comparable to M. C. Escher's work and influenced by the short movie Building, and needs to move forward.
This is also the main challenge regarding gameplay: finding the correct way to move forward (aggravated by the architecture and some false, endless passages) and jumping over gaps.
During lost sprints, the player needs to click in the correct rhythm so the protagonist receives enough air - failing hurts sight and speed. In some occasions, there are puzzles to solve. As the whole game, those heavily rely on light: the player needs to place light spheres (by touching them) which either move obstacles out of the way or make walls pervious with their light.