Omega Five is a horizontal shoot-em-up, spanning four levels. The player can choose between up to four playable characters. Each player has three different upgradable weapons. The game uses a dual-stick control scheme, where the left thumb stick controls the player's movement and the right thumb stick controls the shooting direction. The game has a science fiction theme, however there is no back story explaining the events in the game. The objective is aiming for a highscore, with support for Xbox Live leaderboards and special challenge modes for each level.