Rex the Runt: Lost Marbles is a puzzle game based on Aardman Animations' clay animated TV show Rex the Runt. Rex, Wendy and Big Bad Bob enters Vince's body with a shrunken submarine and have to collect all the marbles to cure his random Pavarotti Disease. In each level there are a number of marbles that need to be collected before escaping through an exit. The gameplay involves walking across floor tiles which are only safe when the player carries a marble of a colour that matches the colour of the floor tile. It is only possible to carry two marbles at a time which means that the marbles have to be collected in the correct order.