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Alien Syndrome is a scrolling shooter.

Your job is to run around and rescue all the captives and make it to the escape hatch before the time bomb explodes. Then face the mother alien at the end of the level.


Alien Syndrome Amstrad CPC Loading screen
Alien Syndrome MSX Killed by the maggot-aliens
Alien Syndrome DOS Opening Title with credits
Alien Syndrome NES Japanese title screen

Promo Images

Alien Syndrome Magazine Advertisement

Alternate Titles

  • "エイリアンシンドローム" -- Japanese spelling

Part of the Following Groups

User Reviews

Sweet cooperative alien-blasting action NES Multimedia Mike (20667)

Critic Reviews

The Games Machine (UK) Atari ST Jul, 1988 92 out of 100 92
Crash! ZX Spectrum Oct, 1988 90 out of 100 90
Classic-games.net NES Jan 13, 2020 7 out of 10 70
Computer and Video Games (CVG) ZX Spectrum Nov, 1989 70 out of 100 70
ST Action Atari ST Sep, 1988 69 out of 100 69
Video Game Den NES Jan 02, 2011 3 Stars3 Stars3 Stars3 Stars3 Stars 60
Ultimate Nintendo: Guide to the NES Library NES 2016 3 Stars3 Stars3 Stars3 Stars3 Stars 60
ACE (Advanced Computer Entertainment) Atari ST Aug, 1988 511 out of 1000 51
Questicle.net NES Jan, 2011 C- 42
Amiga World Amiga Aug, 1989 Unscored Unscored


Topic # Posts Last Post
Published by is incorrect 2 Hergezod (15630)
Jul 07, 2021
Incorrect platform 2 vedder (60495)
May 05, 2019


Sound effect

The opening screen of Alien Syndrome features a digitized sound effect through the PC Speaker. However, the 1-bit method used to reproduce the sound effect is so poor that you can't discern what the sound is supposed to be.
Contributed to by Quapil (5522), Corn Popper (68841), FatherJack (62720), Martin Smith (80322), Terok Nor (33148), Servo (57354), Игги Друге (46309), Katakis | カタキス (43094) and Yakumo (472)
atari 50