Twin Caliber is a co-op third person rail shooter for two players. One plays a police sheriff and the other a hardened criminal. They must band together to unravel a dark mystery around a graveyard full of zombies. Both characters can hold two guns. Each gun is aimed with one of the analog sticks. Points are awarded for killing enemies, particularly multiple at a time from different angles. The game comes with 26 levels, nine level and a handful of different enemies, including zombies, demons, slugs and cultists.
In the German version, all prompts which inform the player about the number of killed enemies, were removed. Also all blood and gore effects on enemies were removed. A detailed list of changes can be found on schnittberichte.com (German).