Jazzpunk is set in a cold war setting. The player takes the role of a secret agent who has to do, well, secret agent stuff like stealing data from the Russians or stealing a person's kidney. The graphics are deliberately crude and all persons are presented like figures from a board game.
From a gameplay perspective, this is an adventure game: the player solves puzzles by using items with other items (or simply by finding the correct item to activate). There are also various mandatory and optional mini games like playing mini golf, participating in a boat race, Galaga or a first-person shooter sequence with a wedding theme. However, the main draw of the game is its non-sequential humour. When exploring the levels, there are many references to discover and many optional items to activate which usually has a humorous consequence.