🐳 29 years ago: The Elder Scrolls: Arena was released!

Alien Syndrome

Description official descriptions

Alien Syndrome is a top down shooter inspired by Sega's original Alien Syndrome action game. The games story takes place thousands of years in the future; by this point in time mankind has explored many parts of the galaxy and established numerous colonies. One such colony, Seti-Alpha 5 (SAT5), has ceased communications for some reason and it is your job to head to SAT5 and investigate what went wrong. Upon arrival, you encounter the alien syndrome, a force which can mutate man and machine into deadly aliens. These events take place roughly 100 years after those in the original Alien Syndrome.

When you begin the game you can select one of several characters as well as choose a character specialty (such as demolitions expert, firebug, seal, tank, and sharpshooter). The specialty you select will determine your initial character stats; as you play through the game you earn levels which provide you points to allocate towards improving your stats. The character stats help determine your characters accuracy in ranged or close attacks, speed, healing power, resistance to fire/radiation, armor strength, and so on.

Similar to the original game, the action is viewed top down. You'll need to explore the numerous corridors and rooms found on SAT5 and eliminate the numerous alien invaders found there. Mission objectives are often provided to you which need to be completed. Additional weapons, ammo, and other useful items can be found throughout the levels. Your character has a limited amount of energy, and if all energy is lost then you will need to begin again at the last checkpoint crossed.

Groups +



Credits (PSP version)

198 People (160 developers, 38 thanks) · View all


Related Games

Alien Syndrome
Released 1988 on Amiga, 1988 on NES, 1989 on DOS...
Alien Syndrome
Released 1987 on SEGA Master System
Alien Syndrome
Released 1992 on Game Gear
Released 2016 on Windows, 2017 on Xbox One, PlayStation 4...
China Syndrome
Released 1982 on Atari 2600
Noir Syndrome
Released 2014 on Android, Linux, Windows
Grief Syndrome
Released 2011 on Windows
Covert Syndrome
Released 2017 on Windows
Syndrome VR
Released 2017 on Windows

Related Sites +

Identifiers +

  • MobyGames ID: 30216


Know about this game? Add your expertise to help preserve this entry in video game history!

Contributors to this Entry

Game added by Servo.

PSP added by samsam12.

Additional contributors: Jeanne, DreinIX.

Last modified February 22nd, 2023.